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Many participants achieve strong results at 9 mg rather than 12 mg, and with a better GI profile

In people with obesity and T2D (SURMOUNT-2 trial), tirzepatide 10 and 15 mg once weekly combined with a moderate intensity lifestyle intervention led to a mean HbA1c reduction of up to 2.1%, with 8487% of the participants achieving HbA1c 6.5% [53]

When used preventively, both in injectable and oral forms, it allows minimizing the occurrence of shoulder joint injuries or alleviating symptoms that occur during their occurrence

Some practitioners start with lower doses around 600-800mg to see how your body responds, then gradually increase if needed